Thermo Fisher Scientific MKL1 Monoclonal Antibody (OTI1B5), TrueMAB
인간 MKL1 단백질(aa 165-397)을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 적합합니다. 1 mg/mL 농도의 액상 형태이며 PBS, BSA, 글리세롤 완충액에 보관됩니다. 세포핵 내 신호 전달 연구 및 근육세포 분화 관련 연구용으로 사용됩니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 165–397 of human MKL1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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