Thermo Fisher Scientific Chromogranin A Polyclonal Antibody
Rabbit polyclonal antibody targeting Chromogranin A for IHC (P) and IHC (F) applications. Recognizes neuroendocrine markers and tumors. Lyophilized form, reconstitutable, stored at 4°C. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic rat chromogranin A (residues 306–314) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2080988 |
Product Specific Information
Reconstitute with 50–100 µL of distilled water, and dilute further in 0.1 M PBS with 1% BSA and 0.1% sodium azide.
Target Information
Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system.
CHGA is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron-specific enolase (NSE) is common in neuroendocrine neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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