Thermo Fisher Scientific ANG Monoclonal Antibody (2A7)
인간 Angiogenin(ANG)을 인식하는 마우스 단일클론 항체로, Western blot 및 ELISA에 적합합니다. 고순도 친화 크로마토그래피로 정제되었으며, PBS 버퍼에 보존제 없이 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A7 |
| Immunogen | ANG (AAH54880, 25 a.a. ~147 a.a) full-length recombinant protein with GST tag (GST MW: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
QDNSRYTHFL TQHYDAKPQG RDDRYCESIM RRRGLTSPCK DINTFIHGNK RSIKAICENK NGNPHRENLR ISKSSFQVTT CKLHGGSPWP PCQYRATAGF RNVVVACENG LPVHLDQSIF RRP
Target Information
Angiogenin (ANG or ANG I) plays a key role in neovascularization and formation of new blood vessels.
It is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that inhibits protein synthesis by hydrolyzing cellular tRNAs.
ANG interacts with endothelial cell-surface actin, potentially influencing cytoskeletal changes.
It is implicated in solid tumor development, and its antagonists can inhibit tumor growth.
Defects in ANG are associated with susceptibility to amyotrophic lateral sclerosis type 9 (ALS9), linking ANG to both ALS and Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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