Thermo Fisher Scientific CFHR1 Polyclonal Antibody
Human CFHR1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 IHC(Paraffin)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer와 glycerol이 포함된 액상 형태로 제공. 연구용으로만 사용 가능.
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- PA558590
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CFHR1. Recombinant protein control fragment (Product # RP-104315) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639724 |
Product Specific Information
- Immunogen sequence: HLEGDTVQII CNTGYRLQNN ENNISCVER
- Highest antigen sequence identity: Mouse - 59%, Rat - 62%
Target Information
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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