Thermo Fisher Scientific Carbonic Anhydrase III Recombinant Rabbit Monoclonal Antibody (006)
Human Carbonic Anhydrase III 단백질을 인식하는 재조합 토끼 단일클론 항체. Western blot 및 Immunoprecipitation에 적합. 보존제가 없는 액상 형태로 제공되며, 높은 특이성과 로트 간 일관성을 제공. 연구용으로만 사용 가능.
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- MA529072
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 006 |
| Immunogen | Recombinant Human Carbonic Anhydrase III/CA3 protein (Met1–Lys260) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785002 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
This antibody is specific for Human Carbonic Anhydrase III (CA3).
Target Information
Carbonic anhydrase III (CAIII) belongs to a multigene family encoding carbonic anhydrase isozymes. These metalloenzymes catalyze the reversible hydration of carbon dioxide and are expressed differently across cell types.
CA3 expression is tissue-specific—high in skeletal muscle, lower in cardiac and smooth muscle. Elevated CA3 levels have been observed in some carriers of Duchenne muscular dystrophy. The CA3 gene spans approximately 10.3 kb and contains seven exons and six introns.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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