
Thermo Fisher Scientific Collagen V Polyclonal Antibody
인체 COL5A1 유래 펩타이드를 면역원으로 한 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 사용 가능. Affinity chromatography로 정제된 액상 항체이며, PBS+50% glycerol에 보관. 내인성 Collagen V α1 검출에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human COL5A1 (Accession P20908), corresponding to amino acid residues G874–R924 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899673 |
Product Specific Information
Antibody detects endogenous levels of total Collagen V alpha 1.
Target Information
COL5A1 encodes an alpha chain for one of the low-abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. COL5A1 product is closely related to type XI collagen, and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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