Thermo Fisher Scientific C5a1, Complement C5a Receptor 1 Polyclonal Antibody
Thermo Fisher Scientific의 C5a1 폴리클로날 항체는 Mouse와 Rat에 반응하며, C5a Receptor 1(CD88)을 표적합니다. Western blot과 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제된 고순도 제품입니다. 연구용으로만 사용됩니다.
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- 7TM0032MN-IC
- 판매단위
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100
Publications
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from the carboxyl-terminal tail identical in mouse and rat C5a1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known.
C5AR1 has been implicated in asthma, and its expression is reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract.
CD88 stimulates chemotaxis, granule enzyme release, and superoxide anion production. It is a component of the classical pathway of the complement cascade and may be involved in tissue injury associated with ischemia or sepsis.
Diseases associated with CD88 include:
- Mannose-Binding Lectin Deficiency
- Systemic Lupus Erythematosus
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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