Thermo Fisher Scientific MAFA Polyclonal Antibody
Rabbit polyclonal antibody against MAFA for WB and ChIP applications. Reacts with human and rat, predicted to react with monkey, mouse, and bovine. Affinity purified, unconjugated, supplied in PBS with BSA and glycerol. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
ChIP assay (ChIP)
- Tested Dilution: 1.5 µg × 10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to Human MAFA (aa 331–343, 28–41) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA, 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633223 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with specific proteins or peptides. The antibody is affinity purified from rabbit sera and tested for functionality in various research applications.
This antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.
Predicted to react with Monkey, Mouse, Rat, and Bovine.
Target Information
MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element regulating pancreatic beta cell-specific expression of the insulin gene. MAFA cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. It can serve as an oncogene or tumor suppressor depending on cell context.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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