Thermo Fisher Scientific ATP8B3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human ATP8B3 (NP_620168.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ATP8B3,uniProtId:O60423-2,ncbiNodeId:9606,antigenRange:600-900,antigenLength:1300,antigenImageFileName:PA5-120588_ATP8B3_O60423-2_Rabbit.svg,antigenImageFileNamePDP:PA5-120588_ATP8B3_O60423-2_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.35 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914160

Product Specific Information

Positive test controls include: HCT116.

Immunogen sequence: VTAARNFGYV FLSRTQDTVT IMELGEERVY QVLAIMDFNS TRKRMSVLVR KPEGAICLYT KGADTVIFER LHRRGAMEFA TEEALAAFAQ ETLRTLCLAY REVAEDIYED WQQRHQEASL LLQNRAQALQ QLLGATAIED RLQDGVPETI KCLKKSNIKI WVLTGDKQET AVNIGFACEL LSENMLILEE KEISRILETY WENSNNLLTR ESLSQVKLAL VINGDFLDKL LVSLRKEPRA LAQNVNMDEA WQELGQSRRD FLYARRLSLL CRRFGLPLAA PPAQDSRARR SSEVLQERAF V

Target Information

P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. May be responsible for the maintenance of asymmetric distribution of phosphatidylserine (PS) in spermatozoa membranes. Involved in acrosome reactions and binding of spermatozoa to zona pellucida.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.