Thermo Fisher Scientific Phospho-PIK3CG (Ser1100) Polyclonal Antibody
Phospho-PIK3CG (Ser1100) 폴리클로날 항체로, 인간 PIK3CG 단백질의 인산화 부위를 특이적으로 인식합니다. Rabbit IgG 기반의 액상 항체이며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. Dot blot 검증 완료, 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Dot blot (DB) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1100 of human PIK3CG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10982254 |
Product Specific Information
This antibody is predicted to react with mouse and porcine based on sequence homology.
Target Information
PIK3CG (p110 gamma) is the sole class IB phosphatidylinositol 3-kinase family member, which along with the class IA family members, generates the important second messenger PIP2. Unlike the class IA enzymes that signal downstream of receptor tyrosine kinases, PIK3CG primarily signals downstream of GPCRs. The gene product phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring and modulates extracellular signals, including those from E-cadherin-mediated cell-cell adhesion, maintaining epithelial integrity. It also plays a role in regulating cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 associated with myeloid leukemias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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