Thermo Fisher Scientific SMC2 Polyclonal Antibody
Thermo Fisher Scientific의 SMC2 Polyclonal Antibody는 인간 SMC2 단백질을 인식하는 Rabbit IgG 항체로, Western blot과 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 용액 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunoprecipitation (IP)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human SMC2 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.17 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736634 |
Product Specific Information
- Positive Control: 293T, A431, HeLa, HepG2
- Predicted Reactivity: Mouse (90%), Rat (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CAP-E and CAP-C (Chromosome Associated Protein-E & C) are SMC (Structural Maintenance of Chromosome) family members forming a heterodimeric complex essential for mitotic chromosome condensation and segregation. The hCAP-C/hCAP-E complex, part of the condensin multiprotein complex, interacts with phosphorylated Histone H3 to facilitate chromosome condensation during mitosis. Distinct distribution patterns of the two heterodimeric complexes in the interphase nucleus suggest independent roles in different aspects of mitotic chromosome organization in human cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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