Thermo Fisher Scientific NXF3 Polyclonal Antibody
Human NXF3 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA551832
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NXF3. Recombinant protein control fragment (Product # RP-92215) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644917 |
Product Specific Information
Immunogen sequence:
NPAGIPHFVH RELKSEKVEQ IKLAMNQQCD VSQEALDIQR LPFYPDMVNR DTKMASNPRK CMAASLDVHE ENIPTVMSAG EMDKWKGIEP GEKCADRSPV CTTFSDTSSN INSILELFPK LLCLDGQQSP RATLCGTEAH KRL
- Highest antigen sequence identity to orthologs:
- Mouse: 45%
- Rat: 41%
Target Information
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family include:
- Noncanonical RNP-type RNA-binding domain (RBD)
- Four leucine-rich repeats (LRRs)
- Nuclear transport factor 2 (NTF2)-like domain (heterodimerization with NXT1)
- Ubiquitin-associated domain (interactions with nucleoporins)
The LRRs and NTF2-like domains are required for export activity. Alternative splicing is common in this gene family.
The encoded protein has shortened LRR and ubiquitin-associated domains, and its RBD is unable to bind RNA. It is located in the nucleoplasm but not associated with the nuclear envelope or nucleolus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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