Thermo Fisher Scientific Phospho-Phospholamban (Ser16, Thr17) Polyclonal Antibody
Phospho-Phospholamban (Ser16, Thr17) 폴리클로날 항체로, 인간·마우스·랫트 시료에 반응합니다. Western blot과 ELISA에 사용 가능하며, Affinity Chromatography로 정제된 고순도 제품입니다. 심근 세포 내 칼슘 펌프 조절 단백질 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around S16 & T17 of human PLN (NP_002658.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.43 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914893 |
Product Specific Information
- Positive test controls include: HeLa, C6
- Immunogen sequence: ASTIE
Target Information
Phospholamban (PLB) is a 52 amino acid phosphoprotein that regulates the calcium pump of cardiac sarcoplasmic reticulum (SR).
PLB forms an oligomer of five identical subunits, each with a cytoplasmic and transmembrane domain.
The cytoplasmic domain (residues 1–25) contains phosphorylation sites, is highly basic, and easily cleaved by proteases.
The transmembrane domain (residues 25–52) is hydrophobic, protease-resistant, and stabilizes the pentamer.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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