Thermo Fisher Scientific Cytokeratin 10 Monoclonal Antibody (DE-K10)

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

View 6 publications 6 publications

Immunohistochemistry (IHC)

-

View 31 publications 31 publications

Immunohistochemistry (Paraffin) (IHC (P))

0.5-1.0 µg/mL

View 5 publications 5 publications

Immunocytochemistry (ICC/IF)

-

View 9 publications 9 publications

in situ PLA (PLA)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Dog, Cat, Human, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

DE-K10

Immunogen

Cytoskeletal preparation extracted from human ectocervical epithelium if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cytokeratin 10,uniProtId:P13645-1,ncbiNodeId:9606,antigenRange:1-584,antigenLength:584,antigenImageFileName:MA5-13705_Cytokeratin_10_P13645-1_House_mouse.svg,antigenImageFileNamePDP:MA5-13705_Cytokeratin_10_P13645-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10979022

Product Specific Information

MA5-13705 targets Cytokeratin 10 in IF, IHC (P), and WB applications and shows reactivity with Canine, Feline, Human, and Rat samples.

The MA5-13705 immunogen is cytoskeletal preparation extracted from human ectocervical epithelium.

Target Information

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e., skin) and non-keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8. 5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.