Thermo Fisher Scientific RTKN Monoclonal Antibody (OTI2E9), TrueMAB
RTKN 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로, Western blot과 IHC(Paraffin)에 적합합니다. HEK293T에서 생산된 full-length human recombinant RTKN을 면역원으로 사용하였으며, carrier-free 형태로 제공되어 다양한 실험 응용에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E9 |
| Immunogen | Full length human recombinant protein of human RTKN produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The RTKN gene encodes a scaffold protein that interacts with GTP-bound Rho proteins, inhibiting their GTPase activity. This regulation affects cellular processes such as cytokinesis, transcription, smooth muscle contraction, cell growth, and transformation. Dysregulation of Rho signaling is associated with various cancers. Alternative splicing generates multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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