Thermo Fisher Scientific CD6 Monoclonal Antibody (C6, 372)
인간 CD6 단백질에 특이적인 마우스 모노클로날 항체로, IHC, ICC/IF, 유세포분석에 적합합니다. 단백질 A/G로 정제된 액상 형태이며, PBS(pH 7.4) 버퍼에 보존됩니다. T세포 활성화 및 CD6-ALCAM 상호작용 연구에 활용 가능합니다.
- 카탈로그번호
- 923-MSM2-P1ABX
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD6 Monoclonal Antibody (C6, 372)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C6, 372 |
| Immunogen | Human recombinant CD6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia (ALL) cells.
It interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and functions as a coreceptor for T cell activation and stabilizer of the immunological synapse.
CD6–ALCAM mediated cell adhesion is important for T cell proliferation. CD6 may also modulate CD5 signaling, contributing to fine-tuning immune responses.
Ligation of CD6 has an anti-apoptotic role in chronic lymphocytic leukemia B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.