Thermo Fisher Scientific RAD23B Monoclonal Antibody (OTI12C10)
RAD23B 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot에 적합. 인간 유래 단백질(aa 1-253)을 항원으로 제작. 1 mg/mL 액상 형태, PBS/BSA/Glycerol 완충액에 보관. -20°C에서 보관하며 동결-해동 반복은 피해야 함.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12C10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–253 of RAD23B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725184 |
Target Information
The protein encoded by the RAD23B gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). It forms part of the protein complex that complements the NER defect of xeroderma pigmentosum group C (XP-C) cell extracts in vitro. RAD23B interacts with and enhances the activity of 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition within base excision repair. The protein also contains an N-terminal ubiquitin-like domain that interacts with the 26S proteasome, indicating a potential role in the ubiquitin-mediated proteolytic pathway.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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