Thermo Fisher Scientific MYOZ2 Polyclonal Antibody
Thermo Fisher Scientific MYOZ2 Polyclonal Antibody는 인간 MYOZ2 단백질을 인식하는 토끼 유래 IgG 항체로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존됩니다. 심장 및 골격근 연구용으로 최적화된 연구 전용 시약입니다.
- 카탈로그번호
- PA557390
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MYOZ2. Recombinant protein control fragment (Product #RP-96741) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644397 |
Product Specific Information
Immunogen sequence:
LEELSHLSNR GARLFKMRQR RSDKYTFENF QYQSRAQINH SIAMQNGKVD GSNLEGGSQQ APLTPPNTPD PR
Antigen sequence identity:
- Mouse: 90%
- Rat: 85%
Target Information
The calcineurin-binding protein Myozenin 2 (calsarcin-1) is a member of the calsarcin protein family. Calcineurin is a calcium- and calmodulin-dependent protein phosphatase involved in controlling slow fiber gene expression in skeletal muscle and cardiac hypertrophy. Calsarcins couple calcineurin and muscle activity by binding calcineurin to α-actinin at the Z-line of the sarcomere.
During embryogenesis, Myozenin 1 and 2 are expressed in developing muscle. The Myozenin 2 gene maps to chromosome 4q and is expressed specifically in adult cardiac and slow-twitch skeletal muscle, while Myozenin 1 is only detected in fast skeletal muscle.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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