Thermo Fisher Scientific WIPI1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat, Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 187-446 of human WIPI1 (NP_060453.3). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:WIPI1,uniProtId:Q5MNZ9-1,ncbiNodeId:9606,antigenRange:187-446,antigenLength:446,antigenImageFileName:PA5-110581_WIPI1_Q5MNZ9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110581_WIPI1_Q5MNZ9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.46 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855992

Product Specific Information

Immunogen sequence: GTLAAITFNA SGSKLASASE KGTVIRVFSV PDGQKLYEFR RGMKRYVTIS SLVFSMDSQF LCASSNTETV HIFKLEQVTN SRPEEPSTWS GYMGKMFMAA TNYLPTQVSD MMHQDRAFAT ARLNFSGQRN ICTLSTIQKL PRLLVASSSG HLYMYNLDPQ DGGECVLIKT HSLLGSGTTE ENKENDLRPS LPQSYAATVA RPSASSASTV PGYSEDGGAL RGEVIPEHEF ATGPVCLDDE NEFPPIILCR GNQKGKTKQS

Target Information

WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles and the trans-Golgi network. It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas and skeletal muscle. WIPI1 is upregulated in a variety of tumors, suggesting a role in carcinogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.