Thermo Fisher Scientific WIPI1 Polyclonal Antibody
WIPI1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 ELISA에 적합합니다. 자가포식 및 단백질 수송 연구에 활용 가능하며, Human, Mouse, Rat 반응성을 가집니다. 액상 형태로 -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 187–446 of human WIPI1 (NP_060453.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.46 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855992 |
Product Specific Information
Immunogen sequence:
GTLAAITFNA SGSKLASASE KGTVIRVFSV PDGQKLYEFR RGMKRYVTIS SLVFSMDSQF LCASSNTETV HIFKLEQVTN SRPEEPSTWS GYMGKMFMAA TNYLPTQVSD MMHQDRAFAT ARLNFSGQRN ICTLSTIQKL PRLLVASSSG HLYMYNLDPQ DGGECVLIKT HSLLGSGTTE ENKENDLRPS LPQSYAATVA RPSASSASTV PGYSEDGGAL RGEVIPEHEF ATGPVCLDDE NEFPPIILCR GNQKGKTKQS
Target Information
WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as ATG18 or WIPI49, is involved in autophagy and may regulate protein trafficking in recycling pathways. It contains three WD repeats and forms a 7-bladed propeller structure that mediates protein interactions. WIPI1 is localized to cytoplasmic vesicles, endosomes, clathrin-coated vesicles, and the trans-Golgi network. It is ubiquitously expressed, with high expression in heart, testis, placenta, pancreas, and skeletal muscle. WIPI1 is upregulated in various tumors, suggesting a role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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