Thermo Fisher Scientific CRP Polyclonal Antibody
인체 및 다양한 종에 반응하는 CRP 폴리클로날 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Protein A로 정제된 고품질 항체로 1 mg/mL 농도의 액상 형태. 염증 반응 및 면역 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human CRP (amino acids 125–224) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
C-reactive protein (CRP) is a major cyclic, pentameric acute-phase protein composed of five identical, noncovalently bound, nonglycosylated subunits. Each subunit contains 206 amino acids with a molecular weight of approximately 24 kDa. CRP is synthesized by the liver, and its plasma concentration increases dramatically during inflammation, infection, or tissue injury.
CRP functions as an initiator of the classical complement cascade, binds to nuclear components such as chromatin and histones, and plays a critical role in innate immunity. It also acts as an opsonin and activator of monocytes/macrophages, facilitating the clearance of pathogens and necrotic cells. Elevated basal CRP levels are associated with increased risk of hypertension and cardiovascular disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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