Thermo Fisher Scientific NR2C2 Monoclonal Antibody (OTI1F3), TrueMAB
NR2C2 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot 및 IHC(P)에서 검증됨. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. 인산완충용액(PBS)과 트레할로스를 포함하며 보존제 무첨가. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:250 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–241 of human NR2C2 produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors.
These proteins contain:
- An N-terminal transactivation domain
- A central DNA-binding domain with two zinc fingers
- A C-terminal ligand-binding domain
The activated receptor/ligand complex translocates to the nucleus, where it binds to hormone response elements of target genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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