Thermo Fisher Scientific PTPRE Monoclonal Antibody (OTI4B2)
Human PTPRE 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, WB, IHC, ICC, Flow Cytometry에 적합. 1 mg/mL 농도의 액상 형태이며, 친화 크로마토그래피로 정제됨. PBS/BSA/glycerol buffer에 보관하며 -20°C에서 안정적 유지.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B2 |
| Immunogen | Full length human recombinant protein of PTPRE produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725154 |
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, known to regulate various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
Two alternatively spliced transcript variants exist:
- One encodes a receptor-type PTP with a short extracellular domain, single transmembrane region, and two tandem intracytoplasmic catalytic domains.
- The other encodes a nonreceptor-type isoform with a distinct hydrophilic N-terminus.
Studies in mice suggest regulatory roles of this PTP in RAS-related signal transduction, cytokine-induced STAT signaling, and activation of voltage-gated K⁺ channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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