Thermo Fisher Scientific RIC8A Monoclonal Antibody (OTI3G3)
RIC8A 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. Western blot, IHC(P), ICC/IF에 사용 가능. Human 반응성, Mouse IgG1 아이소타입. 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G3 |
| Immunogen | Full length human recombinant protein of RIC8A produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.83 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725241 |
Target Information
Guanine nucleotide exchange factor (GEF) that can activate some, but not all, G-alpha proteins. It activates GNAI1, GNAO1, and GNAQ, but not GNAS, by exchanging bound GDP for free GTP. Involved in the regulation of microtubule pulling forces during mitotic chromosome movement by stimulating G(i)-alpha protein, possibly leading to the release of G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing G(q)-coupled receptor-mediated ERK activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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