
Thermo Fisher Scientific PIK3C2B Monoclonal Antibody (OTI3B1), TrueMAB
PIK3C2B 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 IHC(파라핀) 분석에 적합합니다. 인간 시료 반응성이 있으며, 고순도 친화 크로마토그래피 정제 및 안정적 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B1 |
| Immunogen | Full length human recombinant protein of human PIK3C2B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Class II PI3 kinases, including PIK3C2B, phosphorylate the 3 position of PI or PI4P. Although less studied than class I PI3 kinases, class II enzymes are associated with receptor-mediated cellular processes such as insulin signaling, neuronal survival, and growth factor signaling.
Protein kinases transfer phosphate groups from ATP to substrate proteins, mediating signal transduction in eukaryotic cells. They regulate metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation. With over 500 gene products, the protein kinase family is one of the largest in eukaryotes, classified into eight major groups based on catalytic domain sequence comparisons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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