Thermo Fisher Scientific PATE3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total PATE3.

Target Information

PATE3 (prostate and testis expressed protein 3), also known as PATE-DJ or HEL-127, is a 98 amino acid protein containing one UPAR/Ly6 domain and belongs to the PATE family. PATE3 is a secreted protein expressed in the prostate and testis. The gene encoding PATE3 spans approximately 3,490 bases and maps to human chromosome 11p15.5.

Chromosome 11 comprises about 4% of the human genome and is rich in genes associated with various diseases. The ATM gene on chromosome 11 regulates cell cycle arrest and apoptosis following DNA double-strand breaks, and its mutation causes ataxia-telangiectasia. Other notable disorders linked to chromosome 11 include sickle cell anemia, thalassemia, Wilms’ tumor, WAGR syndrome, Denys-Drash syndrome, Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.