Thermo Fisher Scientific PATE3 Polyclonal Antibody
PATE3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(Paraffin)에서 검증됨. Human, Mouse, Rat 시료에 반응하며, Affinity chromatography로 정제된 액상 형태. PBS 및 50% glycerol buffer에 보관, -20°C에서 저장.
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- PA5102606
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PATE3 (Accession B3GLJ2), corresponding to amino acid residues Y12–Q62 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815924 |
Product Specific Information
Antibody detects endogenous levels of total PATE3.
Target Information
PATE3 (prostate and testis expressed protein 3), also known as PATE-DJ or HEL-127, is a 98 amino acid protein containing one UPAR/Ly6 domain and belongs to the PATE family. PATE3 is a secreted protein expressed in the prostate and testis. The gene encoding PATE3 spans approximately 3,490 bases and maps to human chromosome 11p15.5.
Chromosome 11 comprises about 4% of the human genome and is rich in genes associated with various diseases. The ATM gene on chromosome 11 regulates cell cycle arrest and apoptosis following DNA double-strand breaks, and its mutation causes ataxia-telangiectasia. Other notable disorders linked to chromosome 11 include sickle cell anemia, thalassemia, Wilms’ tumor, WAGR syndrome, Denys-Drash syndrome, Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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