Thermo Fisher Scientific FAIM3 Polyclonal Antibody
FAIM3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human 시료에 반응합니다. WB, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능하며, Protein A로 정제된 액상 형태입니다. -20°C에서 보관하며 연구용으로 적합합니다.
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Thermo Fisher Scientific FAIM3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human FAIM3 (amino acids 51–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Apoptosis is an important process by which normal tissue homeostasis and function are maintained. The Fas receptor and its ligand regulate this process, leading to formation of a death-inducing signaling complex containing FADD and activation of caspase-8, which triggers downstream caspases such as caspase-3 and -7. Overexpression of Toso, a regulator of Fas-induced apoptosis in lymphoid cells, renders cells resistant to Fas-induced apoptosis but not to TRAIL-induced apoptosis. Toso associates with FADD, suggesting it disrupts formation of the death-inducing signaling complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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