Thermo Fisher Scientific VAV3 Polyclonal Antibody
VAV3 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 polyclonal 항체. IHC, ICC/IF, Flow Cytometry에 사용 가능. 인간 반응성, 0.5 mg/mL 농도, 액상 형태. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 7.5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (SGEQGTLKLPEK) corresponding to the internal amino acids of VAV3 (aa 567–579) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10987387 |
Product Specific Information
- This antibody is predicted to react with canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
The VAV3 gene encodes a guanine nucleotide exchange factor (GEF) for Rho family GTPases, which activate pathways involved in actin cytoskeletal rearrangements and transcriptional regulation.
VAV3 acts preferentially on RhoG, RhoA, and to a lesser extent, RAC1, associating maximally with nucleotide-free states of these GTPases.
Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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배송 정보
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