Thermo Fisher Scientific ITGB5 Polyclonal Antibody
ITGB5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF에 적합합니다. 인간, 마우스, 랫드, 영장류 시료에 반응하며, 고순도의 액상 항체로 -20°C 보관이 필요합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ITGB5 (Accession P18084), corresponding to amino acid residues A726–K776 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2903090 |
Product Specific Information
This antibody detects endogenous levels of total Integrin beta 5.
Target Information
Integrins are essential extracellular matrix (ECM) receptor proteins located on cell surfaces. They are heterodimers composed of alpha and beta transmembrane glycoprotein subunits. About 22 different integrins (alpha/beta combinations) exist in nature.
Integrins are abundant at the cell surface and bind ligands with low affinity, requiring clustering for effective ECM binding. They interact with various ligands including laminin. Each integrin features a large N-terminal extracellular domain for ECM ligand binding and a small C-terminal cytoplasmic domain that mediates actin cytoskeleton interaction and signaling.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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