Thermo Fisher Scientific RPAP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunoprecipitation (IP)

1-5 µL/mg of lysate

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

E. coli-derived Human RPAP1 fragment

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS, pH 7

Contains

0.03% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2902846

Target Information

RNA polymerases transcribe nuclear genes for ribosomal RNA and are integral components of ribosomal biogenesis. RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA. RNA polymerase II (Pol II) synthesizes mRNA. RNA polymerase III (Pol III) transcribes class III genes, encoding a number of small ribosomal RNA molecules including tRNA and 5S rRNA. RPAP1 (RNA polymerase II associated protein 1) is a 1, 393 amino acid nuclear protein that is thought to connect Pol II to acetylated Histone H3 and regulators of protein complex formation. A member of the RPAP1 family, RPAP1 exists as three alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 15q15.1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.