Thermo Fisher Scientific SPG7 Monoclonal Antibody (OTI1C1), TrueMAB
SPG7 단백질을 인식하는 마우스 단클론 항체로, Western blot, ICC/IF, Flow cytometry 등에 사용 가능. 인간, 개, 생쥐, 랫트 반응성. 무보존제, 동결건조 제형으로 높은 순도와 안정성을 제공. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C1 |
| Immunogen | Human recombinant protein fragment (aa 300–573 of human SPG7) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The SPG7 gene encodes a mitochondrial metalloprotease belonging to the AAA family. These proteins contain an ATPase domain and are involved in various cellular processes such as membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis.
Mutations in SPG7 cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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