Thermo Fisher Scientific POLR3E Polyclonal Antibody
POLR3E 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간 시료 반응성. 액상 형태로 1 mg/mL 농도, PBS와 50% glycerol에 보관. 세포 내 POLR3E 단백질 검출 연구용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human POLR3E (Accession Q9NVU0), corresponding to amino acid residues A84–Q134 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900413 |
Product Specific Information
Antibody detects endogenous levels of total POLR3E.
Target Information
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters.
Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses.
Acts as nuclear and cytosolic DNA sensor involved in innate immune response.
Can sense non-self dsDNA that serves as template for transcription into dsRNA.
The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs), induce type I interferon and NF-κB through the RIG-I pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-115778_POLR3E_Q9NVU0-1_Rabbit.svg)
(이미지 파일명: PA5-115778_POLR3E_Q9NVU0-1_Rabbit_PDP.jpeg)
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