Thermo Fisher Scientific LIG3 Polyclonal Antibody
Thermo Fisher Scientific의 LIG3 Polyclonal Antibody는 인간 DNA Ligase III를 인식하는 고품질 rabbit polyclonal 항체입니다. Western blot 및 immunoprecipitation에 적합하며, DNA 복구 및 재조합 연구에 활용됩니다. 액상 형태로 제공되며 -20°C에서 안정적으로 보관 가능합니다.
- 카탈로그번호
- PA5118033
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 1–5 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human LIG3/DNA Ligase III fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2902637 |
Target Information
There are four distinct ligase proteins found in mammalian cells. The activity of these DNA ligases is required for the joining of DNA strand breaks that occur during DNA replication, repair, and recombination.
DNA Ligase III gene product migrates as a 100 kDa (α-form) protein in somatic tissues, is ubiquitously expressed, and complexes with XRCC-1 and a 97 kDa (β-form) protein that is found in testis.
DNA Ligase III is involved in rejoining DNA single-strand breaks and in the base excision repair pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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