Thermo Fisher Scientific DNAJC1 Polyclonal Antibody
DNAJC1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체로, Western blot과 면역조직화학(IHC)에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS와 글리세롤 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DNAJC1. Recombinant protein control fragment (Product # RP-90265) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640690 |
Product Specific Information
Immunogen sequence:
EDLSQLTRSM VKFPGGTPGR WEKIAHELGR SVTDVTTKAK QLKDSVTCSP GMVRLSELKS TVQNSRPIKT ATTLPDDMIT QREDAEGVAA EEEQEGDSGE QETGATDARP RRRKPARLLE ATAKPEPEEK SRAKRQKDFD IAEQNESS
Highest antigen sequence identity to the following orthologs:
- Mouse: 77%
- Rat: 75%
Target Information
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex.
This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity.
These findings reveal a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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