Thermo Fisher Scientific BTLA Monoclonal Antibody (OTI1E5), TrueMAB
BTLA 단백질을 표적으로 하는 Mouse IgG1 단클론 항체. Western blot에 최적화되어 있으며, HEK293T 세포에서 발현된 full-length human BTLA 항원을 사용하여 제작. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 연구용 전용 제품.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E5 |
| Immunogen | Full length human recombinant protein of human BTLA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
BTLA (B and T-lymphocyte attenuator) is a co-inhibitory receptor belonging to the CD28 superfamily. It functions as a lymphocyte inhibitory receptor, modulating immune responses. BTLA is expressed on most CD4+ and CD8+ T cells, with expression decreasing upon activation. It remains expressed on Th1 cells but not Th2 cells. BTLA interacts with HVEM (herpesvirus entry mediator), a TNF receptor superfamily member, playing a key role in regulating lymphocyte activation and immune homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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