Thermo Fisher Scientific CLCNKB Polyclonal Antibody
Thermo Fisher Scientific의 CLCNKB Polyclonal Antibody는 인간 CLCNKB 단백질을 인식하는 토끼 유래 다클론 항체입니다. Western blot에 적합하며, 고순도의 Affinity Chromatography 정제 제품입니다. PBS와 2% sucrose buffer에 용해되어 있으며, -20°C에서 보관합니다.
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Applications and Tested Dilution
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human CLCNKB (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608599 |
Product Specific Information
- Peptide sequence: MEEFVGLREG SSGNPVTLQE LWGPCPRIRR GIRGGLEWLK QKLFRLGEDW
- Sequence homology:
- Cow: 93%
- Dog: 86%
- Guinea Pig: 93%
- Horse: 100%
- Human: 100%
- Mouse: 93%
- Rabbit: 93%
- Rat: 93%
Target Information
Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which includes at least nine mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB cause autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence), and both expressed in mammalian kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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