Thermo Fisher Scientific B3GALT4 Polyclonal Antibody
Human B3GALT4 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용.
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human B3GALT4. Recombinant protein control fragment (Product #RP-99281) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638415 |
Product Specific Information
Immunogen sequence:
PFPPYASGTG YVLSASAVQL ILKVASRAPL LPLEDVFVGV SARRGGLAPT QCVKLAGATH YPLDRCCYGK FLLTSHRLDP WKMQEAWKLV GGSDGERTAP FCSWFQGVLG ILRCRA
Highest antigen sequence identity to the following orthologs:
- Mouse: 89%
- Rat: 88%
Target Information
This gene is a member of the beta-1, 3-galactosyltransferase (beta3GalT) gene family. These genes encode type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine).
Beta3GalT genes are distantly related to the Drosophila Brainiac gene and contain a single exon coding sequence. They synthesize type 1 carbohydrate chains, whereas beta4GalT enzymes synthesize type 2 chains. The ratio of type 1:type 2 chains changes during embryogenesis.
By sequence similarity, beta3GalT genes fall into at least two groups: beta3GalT4 and four other beta3GalT genes (beta3GalT1–3, beta3GalT5). This gene is located near the ribosomal protein S18 gene and is involved in ganglioseries glycolipid biosynthesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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