Thermo Fisher Scientific FGL2 Polyclonal Antibody
FGL2 단백질을 타깃으로 하는 Rabbit Polyclonal 항체로, Western blot과 유세포분석에 적합합니다. Human 및 Mouse 시료에 반응하며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 면역억제 및 혈전 관련 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Flow Cytometry (Flow) | 1:25 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 338–367 of the C-terminal region of human FGL2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2717326 |
Target Information
Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases where thrombosis plays a pivotal role, such as virus-induced fulminant hepatitis, fetal loss syndrome, and xenograft rejection. Fgl2 is constitutively expressed in cytotoxic T cells and exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. It functions as a serine protease that directly cleaves prothrombin to thrombin and plays a role in the pathogenesis of viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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