Thermo Fisher Scientific MSI2 Recombinant Rabbit Monoclonal Antibody (ARC2341)
MSI2 단백질을 표적하는 재조합 토끼 단클론 항체로, Western blot, IHC, ELISA에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, HEK293 세포에서 발현된 IgG 형식의 항체입니다. 고순도의 액상 형태로 -20°C에서 보관 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2341 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 200–300 of human Musashi-2 (MSI2) (Q96DH6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897934 |
Product Specific Information
- Positive Samples: HeLa, HT-29, PC-12, MCF7, Mouse brain, Rat brain
- Immunogen sequence:
ARGLPYTMDA FMLGMGMLGY PNFVATYGRG YPGFAPSYGY QFPGFPAAAY GPVAAAAVAA ARGSGSNPAR PGGFPGANSP GPVADLYGPA SQDSGVGNYIS
Target Information
Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein localized in the cytoplasm containing two RRM (RNA recognition motif) domains. It is expressed ubiquitously at low levels and functions as an RNA-binding protein that regulates target mRNA expression, contributing to stem cell proliferation and maintenance in the central nervous system. Msi2 undergoes posttranslational phosphorylation and is upregulated following brain injury, indicating a role in tissue regeneration. Chromosomal aberrations involving Msi2 are linked to chronic myeloid leukemia progression. Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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