Thermo Fisher Scientific SQSTM1 Polyclonal Antibody
Human SQSTM1 단백질을 인식하는 sheep polyclonal antibody로, WB 및 IHC(P/F)에 사용 가능. 합성 펩타이드(aa 300-360)를 면역원으로 제작. 동결건조 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:2,000 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:200–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from amino acid region 300–360 of human SQSTM1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 150 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: sequestosome-1.
Target Information
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-κB) signaling pathway.
The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-κB in response to upstream signals.
Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene.
Mutations in this gene result in sporadic and familial Paget disease of bone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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