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Thermo Fisher Scientific p35 Polyclonal Antibody
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Thermo Fisher Scientific p35 Polyclonal Antibody

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p35 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF에 적합. Human, Mouse, Rat에서 반응하며, 항원 친화 크로마토그래피로 정제됨. 신경 발달 및 Alzheimer’s disease 연구에 유용.

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마지막 업데이트 2025. 07. 30. 오전 07:18
Thermo Fisher Scientific PA578263 p35 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
731,200원VAT 포함 804,320원

Thermo Fisher Scientific · Thermo Fisher Scientific p35 Polyclonal Antibody

Applications and Tested Dilutions

Application Tested Dilution
Western Blot (WB) 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P)) 1:100–1:1,000
Immunocytochemistry (ICC/IF) 1:100–1:1,000

Product Specifications

항목 내용
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Human p35. The exact sequence is proprietary.
Conjugate Unconjugated
Form Liquid
Concentration 0.97 mg/mL
Purification Antigen affinity chromatography
Storage Buffer PBS, pH 7, with 20% glycerol
Contains 0.025% ProClin 300
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Conditions Wet ice
RRID AB_2736311

Product Specific Information

  • Positive Control: HeLa
  • Predicted Reactivity: Mouse (100%), Rat (100%), Bovine (100%)
  • Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The p35 protein is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5), essential for proper central nervous system development. p35 is cleaved by calpain to form p25, which relocates from the cell periphery to nuclear and perinuclear regions. The accumulation of p25 in neurons of Alzheimer’s disease patients correlates with increased CDK5 activity and aberrant phosphorylation of tau protein, contributing to disease pathology.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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