Thermo Fisher Scientific CSE1 Polyclonal Antibody
CSE1 단백질을 인식하는 Rabbit Polyclonal Antibody로 다양한 응용(WB, IHC, IP)에 사용 가능. 액상 형태로 1 mg/mL 농도, 4°C 보관. FFPE 조직에서 citrate buffer(pH 6.0)로 epitope retrieval 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (IHC) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 1–50 of human Chromosome Segregation-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
Target Information
Proteins carrying a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha is then returned to the cytoplasm, leaving the NLS protein behind. The encoded protein binds strongly to NLS-free importin-alpha, and this interaction is released in the cytoplasm by RANBP1 and RANGAP1. It may also play roles in apoptosis and cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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