Thermo Fisher Scientific IFITM3 Polyclonal Antibody
IFITM3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, ICC/IF, Flow cytometry에 사용 가능. Human 및 Mouse에 반응하며, 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | – |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
| Immunocytochemistry (ICC/IF) | 1:100 | – |
| Flow Cytometry (Flow) | – | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length human IFITM3 recombinant protein (amino acids 1–133) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.74 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1 M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C for short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547856 |
Product Specific Information
- Recommended positive control: HeLa cells
- Predicted reactivity: Chimpanzee (99%)
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein belonging to the IFITM family. These proteins are induced by type I and II interferons and contain interferon-stimulated response elements (ISREs) in their promoter regions. IFITM proteins are involved in various cellular processes, including anti-proliferative activities and cell adhesion. IFITM3 is a 133 amino acid membrane protein induced by IFN-α and IFN-γ, and its expression can be regulated by TEF-1, Brg-1, and Sp1. Overexpression of IFITM genes has been observed in several cancer cell types, suggesting a potential role in carcinogenesis.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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