Thermo Fisher Scientific ZBED1 Monoclonal Antibody (OTI2H3), TrueMAB
ZBED1 단백질을 인식하는 마우스 단클론 항체로, Western blot과 유세포 분석에 적합합니다. HEK293T 세포에서 발현된 인간 ZBED1 재조합 단백질을 면역원으로 사용했습니다. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도의 액상 제품입니다. -20°C에서 보관하며 동결/해동 반복을 피해야 합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H3 |
| Immunogen | Full length human recombinant protein of human ZBED1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ZBED1, also known as DREF, is the human homolog of the Drosophila protein DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation.
RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in inhibition of S-phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting a role in cell proliferation in human cells.
At least 22 ribosomal proteins possess ZBED1 binding sites in their promoters, and anti-ZBED1 RNAi also resulted in decreased RP gene expression.
Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, which is required for nuclear localization and DNA binding.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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