Thermo Fisher Scientific Runx3 Polyclonal Antibody
Runx3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Mouse 및 Rat 시료에 반응하며 WB와 IHC에 사용 가능합니다. 합성 펩타이드 항원을 기반으로 제작되었으며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Thermo Fisher Scientific Runx3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the internal region of rat Runx3 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The antigen is homologous in mouse.
- Specificity: Runx3.
Target Information
This gene encodes a member of the runt domain-containing family of transcription factors.
A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5-PYGPYGGT-3 found in a number of enhancers and promoters, and can either activate or suppress transcription.
It also interacts with other transcription factors.
Functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer.
Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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