Thermo Fisher Scientific Cytokeratin 14 Monoclonal Antibody (2F11)
Cytokeratin 14 단백질을 인식하는 Rabbit Monoclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 고순도 1 mg/mL 액상 포맷. -20°C 보관, Wet ice 배송. 상피세포 및 암 연구용으로 적합.
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F11 |
| Immunogen | Recombinant human Cytokeratin 14 protein, around C-terminal 150aa (Antigen range: 323–472, UniProt ID: P02533-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes: type I (acidic polypeptides) and type II (basic polypeptides).
Keratin 14 belongs to the type I subfamily of low molecular weight keratins and, in combination with keratin 5, distinguishes stratified epithelial cells from simple epithelial cells. It is useful in identifying squamous cell carcinomas and is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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