Thermo Fisher Scientific URM1 Polyclonal Antibody

Applications

Tested Application

• Immunohistochemistry (Paraffin) (IHC (P))

Tested Dilution

• 1:1,000–1:2,500

Product Specifications

Product Specific Information

Immunogen sequence:
SVEVEFGGGA ELLFDGIKKH RVTLPGQEEP WDIRNLLIWI KKNLLKERPE LFIQGDSVRP GILVLINDAD WELLGELDYQ LQDQDSVLFI STLHG

• Highest antigen sequence identity to orthologs:
  • Mouse: 93%
  • Rat: 94%

Target Information

Following the discovery of protein modification by the small, highly conserved ubiquitin polypeptide, a number of distinct ubiquitin-like proteins (Ubls) have been found to function as protein modifiers as well. These Ubls, which include SUMO, ISG15, Nedd8, and Atg8, function as critical regulators of many cellular processes, including transcription, DNA repair, signal transduction, autophagy, and cell-cycle control. Dysregulation of Ubl-substrate modification and mutations in the Ubl-conjugation machinery are implicated in various human diseases. URM1 is a ubiquitin-like modifier protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.