Thermo Fisher Scientific ARFGAP1 Polyclonal Antibody
ARFGAP1 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체입니다. Western blot, IHC, ICC 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. Human 반응성으로 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ARFGAP1 (Product #RP-99305) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791196 |
Product Specific Information
Immunogen sequence:
DHFQNSNIDQ SFWETFGSAE PTKTRKSPSS DSWTCADTST ERRSSDSWEV WGSASTNRNS NSDGGEGGEG TKKAVPPAVP TDDGWD
Target Information
ArfGAP1 is a 406 amino acid regulatory protein with an Arf-GAP domain involved in activation of the GTPase activity of ADP ribosylation factor (ARF). It promotes hydrolysis of ARF1-bound GTP and is essential for dissociation of coat proteins from Golgi-derived membranes and vesicles, playing a key role in membrane trafficking and vesicle transport. Its activity is stimulated by phosphoinositides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been reported, and ArfGAP1 is ubiquitously expressed in most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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