Thermo Fisher Scientific Artemin Polyclonal Antibody
Artemin 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
- Suggested positive control: human dorsal root ganglia/CNS preparation
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Amino acids GPGSRARAAGARGC of human Artemin (aa 110–123) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_568447 |
Target Information
The protein encoded by this gene is a member of the glial cell line-derived neurotrophic factor (GDNF) family of ligands, which belong to the TGF-beta superfamily of signaling molecules. GDNFs possess neurotrophic properties and have potential applications in gene therapy for neurodegenerative diseases. Artemin supports the survival of various peripheral neuron populations and certain dopaminergic CNS neurons. Its expression near these neurons supports its role in both the PNS and CNS. Artemin acts as a ligand for the RET receptor and utilizes GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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