Thermo Fisher Scientific FABP3 Polyclonal Antibody
인간 유래 FABP3 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며, 열매개 항원 회복 권장. 소와 돼지에서도 반응 예측. 항원 친화 크로마토그래피로 정제된 액상 항체로, 장기 보관 시 -20°C 권장.
- 카탈로그번호
- PA519741
- 판매단위
- pk
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Applications and Tested Dilution
- Western Blot (WB): 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 100–200 of Human Cardiac FABP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10988516 |
Product Specific Information
- Heat-mediated antigen retrieval is recommended prior to tissue staining.
- This antibody is predicted to react with cow and pig based on sequence homology.
Target Information
Fatty acid binding proteins (FABP) are small (approximately 13–14 kDa) intracellular proteins with high tissue specificity. FABPs bind long-chain fatty acids and play a key role in intracellular fatty acid utilization. There are at least six distinct types of FABP, each showing specific tissue expression patterns.
FABP leaks rapidly from damaged or dying cells, leading to elevated serum levels. Liver FABP serves as a sensitive marker for hepatocellular damage both in vitro and in vivo. Damaged tissues typically show reduced FABP presence, aiding histological identification. L-FABP is also used as a marker for rapid hepatocyte lysis in toxicology assays and for detecting liver damage during and after transplantation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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