Thermo Fisher Scientific Phospho-PKA beta (Ser338) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000
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ChIP assay (ChIP)

• Tested Dilution: 1:100
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Product Specifications

Product Specific Information

Antibody 44-992G has been used successfully in the ChIP analysis of PKA beta pS338.

Target Information

The catalytic subunit C-beta of PKA (PRKACB) belongs to the Ser/Thr protein kinase family. The PKA catalytic subunit consists of three gene products: C-alpha, C-beta, and C-gamma, and is mapped to human chromosome region 1p36.1. PRKACB is derived from a gene distinct from C-alpha and shows tissue-specific expression. At the amino acid level, C-alpha and C-beta show 93% homology.
The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.