Thermo Fisher Scientific Phospho-PKA beta (Ser338) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 1 publication 1 publication

ChIP assay (ChIP)

1:100

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Product Specifications

Published species

Bacteria

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human PKA catalytic b subunit that contains serine 338. The sequence is conserved in cow and pig. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PKA beta,uniProtId:P22694-1,ncbiNodeId:9606,antigenRange:338,antigenLength:351,antigenImageFileName:44-992G_PKA_beta_P22694-1_Rabbit.svg,antigenImageFileNamePDP:44-992G_PKA_beta_P22694-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533818

Product Specific Information

44-992G has been used successfully in the ChIP analysis of PKA beta pS338.

Target Information

The catalytic subunit C-beta of PKA (PRKACB) is a member of the Ser/Thr protein kinase family (the PKA catalytic subunit consist of three gene products: C-alpha, C-beta, and C-gamma) and has been assigned to human chromosome region 1p36.1. PRKACB is derived from a gene distinct from C-alpha and shows tissue-specific expression. At the amino acid level C-alpha and C-beta showed 93% homology. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.